Intravitreal injection of therapeutic agents.
Peyman GA et al（USA)
Retina 29(7): 875-912, 2009
・硝子体内注入量についてMEDLINEデータベースから654の文献をまとめた
| Antibiotics | Intravitreal | Vitreous | |
| Dose(mg) | Half-lief(h) | ||
| Aminoglycosides | |||
| Amikacin | 0.4 | 24 | |
| Gentamicin | 0.2 | 12-35 | |
| Kanamycin | |||
| Netilmicin | 0.25 | 24 | |
| Streptomycin | |||
| Tobramycin | 0.2 | 16 | |
| Penicillins | |||
| Ampicillin | 5 | 6 | |
| Azlocillin | |||
| Carbenicillin | 0.5-2 | 10-20 | |
| Cloxacillin | |||
| Dicloxacillin | |||
| Methicillin | 2 | 3-5 | |
| Mezlocillin | |||
| Oxacillin | 0.5 | ||
| Penicilln G | 0.2-0.3 | 3 | |
| Piperacillin | 1.5 | ||
| Ticarcillin | 3 | ||
| Cephalosporins | |||
| Cefamandole | 0.08 | 0.5 | |
| Cefazolin | 0.5-2.0 | 7 | |
| Cefotaxime | 0.4 | ||
| Cefotetan | 1 | ||
| Cefoxitin | |||
| Ceftazidime | 2 | 16 | |
| Ceftriaxone | 2 | 12 | |
| Cephalexin | 3 | ||
| Cephaloridine | 2.5 | ||
| Cephalothin | 2 | 2.4 | |
| Moxolactam | 1.25-2.0 | 20 | |
| Fluoroquinolones | |||
| Ciprofloxacin | 0.1 | 5 | |
| Garenoxacin | 0.1-2 | ||
| Gatifloxacin | 0.4 | ||
| Levofloxacin | 0.625 | ||
| Moxifloxacin | 0.05-0.16 | 1.72 | |
| Norfloxacin | |||
| Ofloxacin | 0.05 | 5.65 | |
| Pefloxacin | 0.2 | 3 | |
| Travofloxacin | 0.025 | ||
| Macrolides | |||
| Erythromycin | 0.5 | 30 | |
| Clarithromycin | 1 | 2 | |
| Lincosamides | |||
| Lincomycin | 1 | 7-8 | |
| Clindamycin | 0.5-1 | ||
| Carbapenems | |||
| Imipenem | 0.5 | ||
| Meropenem | |||
| Glycopeptides | |||
| Vancomycin | 1 | 30 | |
| Teicoplanin | 0.75 | ||
| Miscellaneous | |||
| Aztreonam | 0.1 | 7.5 | |
| Chloramphenicol | 2 | 10 | |
| Cotrimoxazole | 1.6 | ||
| Doxycycline | 0.125 | ||
| Chloramphenicol | 1 | ||
| Antifungals | |||
| Amphotericin B | 0.005-0.01 | 6.9-15.1 | |
| Natamycin | 3 x 0.025 | ||
| Nystatin | 200 U | ||
| Azoles | |||
| Fluconazole | 0.1 | 3.1 | |
| Itraconazole | 0.01 | ||
| Ketoconazole | 0.54 | ||
| Miconazole | 0.025-0.05 | 2 | |
| Oxiconazole | 0.1 | ||
| Terconazole | 10 | ||
| Voriconazole | 0.05-0.1 | 2.5 | |
| Echinocandins | |||
| Caspofungin | 0.1 | ||
| Miscellaneous | |||
| Faeriefungin | 0.1 | ||
| Flucyiosine | 0.1 | ||
| Cilofungin | 0.32 |
